Biochem7 - Midterm 2 = Monday, July 19th Only on...

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Midterm 2 = Monday, July 19th Only on Biochemistry Bring pencils / erasers / ID Last names A to M = CHEM 1179 Last names N to Z = BRDA 1610
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A more realistic look at chemical reactions Let’s talk about chemical “kinetics” the rates at which reactions occur All related to “ activation energy”
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Figure 6-8 Activation energy initiates reactions E a = activation energy
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The rate at which a reaction proceeds depends upon how big of an activation energy it must overcome So, even if the overall energetics are favorable (i.e., Δ G < 0), the reaction could go really, really slowly if the activation energy is big. In fact, most biologically important reactions go too slow for life to be possible…. What is the solution to this problem? ENZYMES
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An effective way to speed up a reaction in a living system = lower energy barrier Enzymes = biological catalysts that speed up a reaction without being permanently altered by that reaction Enzymes speed up reactions by lowering the activation energy Enzymes can’t make the impossible occur But they do make the possible occur faster
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Figure 6-10 Enzymes lower the energy barrier Enzymes speed up reactions by reducing activation energies
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Figure 6-9 Enzyme and substrate…. .specificity Specificity of enzyme = due to exact 3D shape of its active site
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Figure 6-11 Life at the active site Orientation Strain Adds charges
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Watch Substrate-Enzyme Movie Animation 06-01
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This note was uploaded on 10/16/2010 for the course MCDB MCDB 1A taught by Professor Senghuilow during the Spring '09 term at UCSB.

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Biochem7 - Midterm 2 = Monday, July 19th Only on...

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