08_FINAL_EXAM_KEY

# 08_FINAL_EXAM_KEY - EEMB 129 2008 FINAL EXAM Name Perm 1(15...

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EEMB 129 - 2008 FINAL EXAM Name__________________ Perm # 1. (15 pts). Here are three human pedigrees. The black symbols represent an abnormal phenotype inherited in a simple Mendelian manner. a) For each pedigree, state whether the abnormal condition is dominant or recessive. State your reasoning. b) In each pedigree, describe the genotypes of as many individuals as possible A. B. C. aa aa aa aa Aa Aa Aa Aa A- AA (Most likely – if were a het, unlikely that none of six offspring would be affected) A- Aa Aa Aa Aa Aa Aa Aa Recessive aa aa aa Aa Aa Aa Aa Aa aa Aa Aa Aa Aa Either: <-Recessive <-Dominant aa Aa Aa aa aa Aa aa Aa aa Aa aa aa aa Aa aa aa aa Dominant

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EEMB 129 - 2008 FINAL EXAM Name__________________ Perm # 2. (10 pts) A. What is the formula for calculating a X 2 statistic? (Obs-Exp) 2 Exp B. If you used X 2 to test whether or not a population was in Hardy-Weinberg equilibrium at a particular locus and obtained the following values, what would you conclude? X 2 = 6.18, df = 2 P < 0.05 so I would conclude that the population was not in Hardy-Weinberg equilibrium. You may use the following table: P df 0.995 0.975 0.9 0.5 0.1 0.05 0.25 0.01 0.005 1 0.000 0.000 0.016 0.455 2.706 3.841 5.024 6.635 7.879 2 0.010 0.051 0.211 1.386 4.605 5.991 7.378 9.210 10.597 3 0.072 0.216 0.584 2.366 6.251 7.815 9.348 11.345 12.838 4 0.207 0.484 1.064 3.357 7.779 9.488 11.143 13.277 14.860 3. (10 pts total) In corn, the allele A allows the deposition of anthocyanin (blue) pigment in the kernels (seeds), while aa plants have yellow kernels. At a second gene, the allele R produces smooth kernels, while rr kernels are wrinkled. A plant with blue smooth kernels was crossed to a plant with yellow wrinkled kernels. The F 1 generation consisted of 1227 blue smooth, 232 blue wrinkled, 268 yellow smooth, and 1273 yellow wrinkled. (10 pts) a) Are the ‘a’ and ‘r’ loci linked? If so, how far apart are they? (4 pts) blue, smooth X yellow, wrinkled Aa, Rr aa, rr Obs expect Exp # Gamete Type 1227 blue, smooth Aa, Rr 1 750 parental 232 blue, wrinkled Aa, rr 1 750 recomb 268 yellow, smooth aa, Rr 1 750 recomb 1273 yellow, wrinkled aa, rr 1 750 parental 3000 (232 + 268)/3000 = 500/3000 = 0.167; 16.7 mu b) What was the genotype of the blue smooth parent? Include the chromosome arrangements of alleles. (3 pts) AR/ar c) If a plant grown from a blue wrinkled F 1 seed is crossed to a plant grown from a yellow smooth F 1 seed, what kinds of kernels would be expected, and in what proportions? (3 pts) Ar/ar x aR/ar Note that in this case, crossing over does not create gametes of new genotypes
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