Analysis of Analgesics - medium longer so they won’t...

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Analysis of Analgesics A. Data presentation Samples Distance traveled (cm) R f Aspirin 27mm 0.6 Acetaminophen 15mm 0.33 Ibuprofen 29mm 0.64 Naproxen 25mm 0. Coffeine 4mm 0.089 Drug Name Analgesics Found R f Values Acetaminophen/aspirin/caffeine Aspirin Caffeine 0.60 0.089 Data Analysis In the process of Bayer testing, there are two unknown dots in the plane; base on the measurement, one of the dot travels 27mm long. Using the formula we get the R f is 0.6 And also, another dot is 4mm and the R f is 0.089. c. Conclusion Thin layer chromatography (TLC) is used to separate similar compounds. According to the theory that on polar medium, more polar compounds will adsorb or cling to the
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Unformatted text preview: medium longer, so they won’t travel as far. Molecules are retained more or less based on their polarity; the most non-polar species go the farthest and the most polar go the least distance. Thus, when we repeat the experiment at the same condition, the R f value for a same ingredient should be exactly the same. However, I think the Thin-layer Chromatography has it own limitations. For instance, if the concentration of a ingredient in the tablet is too low, the dot wont show in the plane....
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