Long Answers 2.

Long Answers 2. - Question1 :AgeneconsistsofDNA...

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Question 1
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Explain at least two reasons why the following definition of a gene is inadequate: “A gene consists of DNA  sequences that are transcribed into a single RNA molecule that encodes a single polypeptide.” - No text entered - Question 2 Genetic material must replicate faithfully. Describe how the double-stranded structure of DNA gives it this property. - No text entered - Question 3 A segment of DNA from Drosophila melanogaster has the sequence:       5’ TCA AGC TTA AGA AGG CAT TTT 3’        (i) Assuming that this is the template strand, what is the sequence of the encoded mRNA (make sure to denote 5’ and 3’  ends of the transcript)? (ii) If this sequence is the coding strand, what is the sequence of the encoded mRNA? - No text entered - Long Answer Section Question 1 You learn that a Mars lander has retrieved a bacterial sample from the polar ice caps. You obtain a sample of this bacteria  and perform the same kind of experiment that Meselson and Stahl did to determine how the Mars bacteria replicates its  DNA. Based on the following equilibrium centrifugation results, what type of replication would you propose for this new  bacteria? Dispersive Model Question 2 A number of scientists have become interested in telomerase as a drug target. Why would they be interested in telomerase? How might cancer drug therapies that target telomerase work? telomerase has been associated with aging and cell death. Thus, by controlling this part by making it a target for the drugs,  we can create a drug against cancer.  The drugs may target these sequences and deactivate in a way so that they can send signals for cell death. This way,  cancer cells can be controlled. Question 3 What does “proofreading” refer to with regard to DNA replication? It is the mechanism to override any errors that might have accrued over the process of DNA replicaiton
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Question 1 How does bacterial DNA differ from eukaryotic DNA? The bacterial DNA is located on the circular chromosome while, the eukaryotic DNA is located on sister chromatids. Thus,  bacterial DNA is less in amount as compared to eukaryotic DNA. Question 2 What happens to a chromosome that loses its centromere? If the chromosome does not have a centromere, the chromosome cannot bind to kinetochore in the cell cycle and thus does  not separate during anaphase. Question 3 How did the work of Hershey and Chase contribute to the model of DNA as the genetic material?
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