pKa_of_common_functional_groups (2)

pKa_of_common_functional_groups (2) - pKa ROH 1618 H 2 35 H...

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CHM 2120 – Approximate pKa’s of Common Functional Groups Notes : - The lower the pKa, the stronger the acid - pKa value is quoted for the underlined “H” - The first 2 tables should be memorized, as well as the groups bearing a “*”. *Strong acids: Acid pKa Acid pKa H Br -9 H 2 SO 4 -9 H Cl -7 H NO 3 -1.4 H F 3 *Common organic functional groups: Note: pKa value is quoted for the visible “H” Functional group pKa Functional group
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Unformatted text preview: pKa ROH 1618 H 2 35 H 2 O 15.7 CH 4 50 R OH O 5 R H 45 NH 3 38 H R 25 R NH 2 O 15 Protons alpha to carbonyls: Functional group pKa Functional group pKa * R CH 3 O 20 Me C H 2 O O Me 9 RO CH 3 O 25 MeO C H 2 O O Me 11 MeO C H 2 O O OMe 13 Protonated species: Functional group pKa Functional group pKa H 3 O +-1.7 *NH 4 + 9 R-OH 2 +-2 -4 Et 3 NH + (R 3 NH + ) 11 R CH 3 O H-3 N H 5 R OH O H-8...
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This note was uploaded on 10/24/2010 for the course SCIENCE 2776 taught by Professor Dr.alisonflynn during the Fall '10 term at University of Ottawa.

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