CHE130A Quiz 2 W10 Hague

CHE130A Quiz 2 W10 Hague - Last Name First Name Quiz#2 Chem...

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Last Name: First Name: Quiz #2 January 25, 2010 Chem 130A Winter 2010 Shown below is Topotecan (trade name Hyacamtin) – a chemotherapeutic agent, developed by GlaxoSmithKline, that is a toposiomerase I inhibitor. N HO N N O O O HO (a) Please label all good hydrogen bond acceptors as HBA in Topotecan. (b) Please label all good hydrogen bond donors as HBD in Topotecan. (c) Please suggest a modification you might make to Topotecan that uses a
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