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Unformatted text preview: BIS103-001 (Spring 2007) May 15, 2007 Midterm #2 Student Name _______________________ Instructor: Oliver Fiehn Student ID #__________________ A- group Please, check appropriate box below. Undergraduate student Open enrollment Completing incomplete Graduate student This exam consists of 32 questions. A maximum of 100 points can be earned. Partial credit will be given. There are a total of 9 pages, including the cover page If you need more space, use the back of pages. Write your name on top of each page! Multiple choice answers may be given negative credits if incorrectly answered. Avoid guessing! Petitions for regarding will be considered only if you have used permanent ink, unless an addition error has occurred. *IT IS YOUR RESPONSIBILITY TO WRITE LEGIBLE! No extra effort will be made to decipher your handwriting. I,_______________________________________, authorize the University to distribute publicly this graded exam (e.g., handed out in class or left in a bin for pick up). I am aware of the fact that violations of the Academic Code of Conduct 1 may be reported to UC Davis Student Judicial Affairs. 1 Examples of academic misconduct include: receiving or providing unauthorized assistance on examinations, using unauthorized materials during an examination, altering an exam and submitting it for re-grading, or using false excuses to obtain extensions of time ( http://sja.ucdavis.edu/cac.htm ). Signature________________________________________ Date_____May 15, 2007___ BIS103-001 (Spring 2007) May 15, 2007 Midterm #2 Student Name _______________________ Instructor: Oliver Fiehn Student ID #__________________ A- group 1. 3 points Mark the incorrect answer on the function of glycogen debranching enzyme in glycogenolysis. A) The debranching enzyme transfers an ! (1 " 4) linked trisaccharide unit from an ! (1 " 6) branch point to the nonreducing end of another branch B) The debranching enzyme produces more ! (1 " 4) linked glucose residues, which are available for phosphorolysis C) The debranching enzyme has a separate active site to hydrolyze the single remaining ! (1 " 6) linked glucose D) The debranching enzyme works as rapid as phosphorylase, thus facilitating seamless release of glucose from glycogen during heavy exercise E) all of the above is correct 2. 3 points Glycogen storage diseases are inherited disorders of glycogen metabolism. For example, von Gierke's Disease is caused by a deficiency of liver glucose-6-phosphatase and results in an enlarged liver and low blood sugar. Mark the correct biochemical explanation for this disease. A) Glucose-6-phosphatase is an important step in UTP-glucose formation. Without that activation of glucose, glycogen balancing is disturbed and the liver increases....
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