October 6 - October 6, 2010 Lecture 12 Genes, Genomics and...

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October 6, 2010 Lecture 12 – Genes, Genomics and Chromosomes – Transposable Elements Protein coding genes take up over half of the human genome Only the exons, it is less than 2 percent Gene duplication is an important process in evolution. New gene copies can either evolve a new function or, alternatively, degenerate over time, (pseudogenes). Many genes code the beta subunit of hemoglobin Recombination occurs between the parental chromosomes, if the two chromosome do not cross over correctly one recombinant chromosome may have 2 copies and the other none. Gamma subunits are only expressed in fetal tissue o Have a higher affinity for oxygen Secondary gene can lose its function o Relic sequence in the genome that is non-functional that leads to termination codons Look like globin gene sequences but are unable to form a protein product o Pseudogenes or develop a more specialized function Structural RNAs many copies of this gene important right after fertilization needs to produce lots of rRNA
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This note was uploaded on 10/23/2010 for the course BIOL BIOL 200 taught by Professor Bureau during the Fall '09 term at McGill.

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October 6 - October 6, 2010 Lecture 12 Genes, Genomics and...

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