September 3 - September 3, 2010 Biol 200 Protein Structure...

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September 3, 2010 Biol 200 Protein Structure and Function E. coli Generation time can be around 20 minutes in a rich medium Central Dogma of Biology o DNA RNA Protein o Genetic information is stored as DNA, is passed through and intermediate, RNA, the information eventually is expressed as a protein DNA (Transcription) RNA Types of RNA o rRNA o tRNA o mRNA o miRNA o RNAi RNA (Translation) Protein Proteins o Catalysis – catalyze intra- and extracellular chemical reactions o Structural – structural rigidity o Transport – flow of materials across membrane o Regulatory – sensors/switches to control protein activity and gene function o Signaling – transmit external signals to cell interior o Motor – motion (muscles primarily formed of actin and myocin (proteins) and their reactions allow for motion) Shape endows the protein with many of its properties o Glutamine synthetase’s shape allows it to bind glutamate and ammonia to make glutamine o Hemoglobin’s shape allows it to bind oxygen
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This note was uploaded on 10/23/2010 for the course BIOL BIOL 200 taught by Professor Bureau during the Fall '09 term at McGill.

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September 3 - September 3, 2010 Biol 200 Protein Structure...

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