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Unformatted text preview: Beaks in Darwins Finches- Group of organisms that Darwin studied as a young man- Found that each of the Galapagos islands had their own distinctive flora and fauna o Different species, but still kind of similar, as if they had shared a recent common ancestor- When Darwin started this voyage, he thought he was going to be a geologist o Recognized that the islands are pretty young, younger than the mainland o Endemic Idea is to connect proximate methods to other evolutionary forces- Cant really do that with a model organism in a lab Words to know:- Mesenchyme o Consists of unspecialized cells- Bmp4 o Signaling molecule that is important for early differentiation in the embryo- Morphological variation:- Growth factors- Craniofacial development- In situ hybridization- RCAS: replication competent avian - Basement membrane: sheet of fibers that anchor down the epithelium- Ectoderm: outer layer of the embryo- Mis-expression- Cis-regulator Why did they want to study bmp4?- Expression in the mesenchyme of upper beaks is correlated with deep and broad beak morphology- Misexpression of bmp4 in chicken embryos causes morphological transformations...
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