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Unformatted text preview: Zone of Polarizing Activity : area of mesenchyme that contains signals which instruct the developing limb bud to form along the anterior/posterior axis AER and ZPA are dependent on each other Hypopheses : feature of the cervical region Apical ectodermal ridge (AER): thickened layer of ectodermal cells at the distal tip of a developing limb bud works with the zone of polarizing activity crucial organizing region during limd development all other vertebrae except amphibians use this ridge Contralateral : on the other side Mesenchyme : mesodermal tissue that develops into connective and skeletal tissues...
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- Fall '10