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Unformatted text preview: N-Boc valine (below). When H 2 SO 4 is used in place of HBr in Boc de-protection reactions, 2-methylpropene is observed instead of 2-bromo-2-methylpropane. Explain with a partial mechanism. An amino acid can readily be converted into an N-acetyl amino acid using acetic anhydride. Why is this not a viable alternative to Boc or Cbz protection for peptide synthesis? N H OH O O O HBr H 3 N OH O + CO 2 + Br H 3 N O O O O O N H OH O O NEt 3 (as a base) 1. 2. H 3 O +...
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