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Unformatted text preview: Practice Problem 5‐27 – Answer Discuss the different experimental conditions used to give the major and minor product distributions shown. KINETIC CONTROL – the product is formed via the less stable enolate (less highly substituted double bond). Excess LDA is used to form the less stable kinetic enolate from a nonsymmetric ketone. THERMODYNAMIC CONTROL – the product is formed via the more stable enolate (more highly substituted double bond). Excess ketone is used to form the more stable thermodynamic enola...
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This note was uploaded on 10/25/2010 for the course CH 310n taught by Professor Iverson during the Summer '08 term at University of Texas at Austin.
- Summer '08