Unformatted text preview: The mechanism for formation of this hydrazone via reaction of hydrazine with the ketone starting material UNDER BASIC REACTION CONDITIONS is outlined below. Complete this mechanism by drawing curved arrows to show movement of electron pairs, and by drawing structures for each “missing” reaction intermediate. Ph C CH 3 O NH 2 NH 2 OH H OH OH OH Hydroxide departs as a leaving group - heating is required to overcome the activation barrier (a "strong" base is typically a "poor" leaving group) Ph C CH 3 N N H 2 H OH Ph C CH 3 O N NH 2 H H Ph C CH 3 O N NH 2 H Ph C CH 3 O N NH 2 H H...
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This note was uploaded on 10/25/2010 for the course CH 310n taught by Professor Iverson during the Summer '08 term at University of Texas.
- Summer '08