Unformatted text preview: As usual, be sure to show structures of all important reaction intermediates. If an intermediate is a resonance hybrid, it is only necessary to draw the most important contributing resonance structure. You may assume that hydronium (H 3 O + ) is the acidic species that reacts with the ester – it is not necessary to show how H 3 O + is generated under the given reaction conditions. OCH 2 CH 3 O OH O CH 3 CH 2 OH H O H H OCH 2 CH 3 O H O H H (plus resonance) OCH 2 CH 3 HO O H H O H H OCH 2 CH 3 HO OH H O H H HO OH O H CH 2 CH 3 O H H OH O H O H H (plus resonance) H O H H...
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- Summer '08
- Amide, acid-catalyzed ester hydrolysis