October 11 lecture - October 11 2010 The Chromosome Theory...

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October 11 2010 The Chromosome Theory of Inheritance Today’s questions: What is the physical basis of Mendel’s rules? What sources of genetic variation occur in nature, other than the existence of more than one allele per gene? I. Pattern and Process componenents of the chromosome theory II. Testing the chromosome theory III. Linkage Q1. What is the key event that makes mitosis produce diploid daughter cells, instead of being a reduction division like meiosis? *homologs go to the metaphase plate independently of each other I. The chromosome theory of inheritance Pattern: Mendel’s rules-principle of segregation/independent assortment Process: Meiosis Key Claim: Genes are found on chromosomes Proposition#1: The principle of segregation results from the separation of homologous chromosomes at meiosis I Draw this for an individual with the phenotype Pp. NOT P||p NOT Pp|| YES P|| ||p Proposition #2: The principle of independent assortment occurs because maternal and paternal chromosomes line up (assort) independently at metaphase of meiosis I. Draw this for an individual with the genotype PpTt.
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This note was uploaded on 10/26/2010 for the course BIOL 180 taught by Professor Freeman during the Fall '07 term at University of Washington.

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October 11 lecture - October 11 2010 The Chromosome Theory...

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