CVS Diseases L19

Cvs diseases l19

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Unformatted text preview: 4/15/10 •  A
heart
a(ack,
or
myocardial
infarc4on
(MI),
is
the
death
of
 a
por4on
of
the
heart
muscle
due
to
a
lack
of
oxygen
 –  Blood
flow
to
the
heart
muscle
cells
is
blocked
 –  Plaque
in
a
coronary
artery
occludes
the
blood
flow
 –  Cells
die,
get
replaced
with
scar
4ssue
(non‐contrac4ng)
 if
it
survives
 •  Heart
failure,
arrhythmias
 Heart
A(ack
 •  Caused
by
Coronary
Artery
Disease
(CAD)
 –  Fa(y
material
(plaque)
builds
up
on
inside
walls
of
 arteries,
can
rupture
or
tear
 –  While
the
plaque
is
forming
and
blood
flow
is
 diminishing,
the
heart
4ssue
may
act
like
a
cramped
 muscle
(Angina)
 Heart
A(ack
 Symptoms:
 Angina
 –  this
“stable
angina”
can
be
treated
by
reducing
ac4vity
 and/or
quiNng
smoking
 –  unstable
angina
appears
with
no
apparent
s4mulus
and
 is
oOen
early
warning
of
impending
heart
a(ack
 •  Shortness
of
breath
 •  Palpita4ons
 •  Swea4ng
and
anxiety
(doom
 •  25%
have
no
symptoms
 Diagnosis:
 ECG
 Chest
X‐ray
(damage)
 Blood
tests
(crea4ne,
troponin)
 Nitrate
drugs,
such
as
nitroglycerine
and
isosorbide
(relax
 cardiovascular
smooth
muscle)
 –  as
the
sm...
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This note was uploaded on 10/27/2010 for the course BIOL 125 taught by Professor Klein during the Spring '10 term at CUNY Hunter.

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