Chapter 15 Fat-Soluble Vitamins

Chapter 15 Fat-Soluble Vitamins - Chapter 15 Fat-Soluble...

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Chapter 15 Fat-Soluble Vitamins *Discovery of Vitamins 1. C. Eijkman -showed that polished rice caused beriberi in chickens and nonpolished rice cured the disease. fed white rice; the technician brought the brown rice and the beriberi went away 2. F.G. Hopkins -showed that tiny amounts of certain factors from milk (has fat)were necessary for the growth of rats on a purified diet 3. Casimir Funk (1920-1930, Novel Prize) -summarized the requirement for “vital amines” in the diet (in addition to CHO, protein and fat); -postulated “vital amine” theory of disease, i.e. certain foods could cure diseases; -4 specific “vital amines” (vitamines) would cure: -pellagra, beriberi, scurvy, rickets. *E.V McCollum- purify diet; took all the coo rout of the bile 1. fat-soluble substance A -using egg yolk to separate this substance 2. Vital amine A 3. Vitamin A *Sir Edward Mellanby- Industrial Revolution -Rickets: in dogs fed an oatmeal diet and kept out of sun -cured rickets with cod liver oil -Discovered the anti=rachitic substance (Vitamin D) since he was a chemist, he noticed that it was not vitamin A *Digestion of Fat-Soluble Vitamins 1. Fat-soluble vitamins require bile acids for absorption 2. Fat-Soluble vitamins require digestive enzymes for absorption
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This note was uploaded on 10/28/2010 for the course NST 114 taught by Professor Cassida during the Fall '10 term at Berkeley.

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Chapter 15 Fat-Soluble Vitamins - Chapter 15 Fat-Soluble...

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