BIOL0131_L1 handout_2009

BIOL0131_L1 handout_2009 - Basic Medical Microbiology...

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1 Basic Medical Microbiology BIOL0131 Lecture 1: A review of signiFcant advances during the history of medical microbiology Medieval engraving of persons infected with bubonic plague Medieval ‘treatment’ for bubonic plague ! ±irst - let me introduce the structure of this course • There are 12 lectures, held at 2pm each ±riday – Lectures 1-7, 9, 10: Dr Pointing – Lecture 8: Dr Smith (±ac. Medicine) – Lectures 11, 12: Dr W.C. Yam (±ac. Medicine) • The coursework is in the form of a poster presentation – Instructions are on the course website Lecture titles 1. A review of signiFcant advances during the history of medical microbiology 2. The ‘normal’ human microbial ²ora 3. Immune responses to infection 4. Host-parasite interactions 5. Spread and control of infection: sterilization and disinfection 6. Spread and control of infection: epidemiology of infectious diseases 7. Antibacterial and antiviral agents, microbial resistance 8. Case studies in disease I: In²uenza 9. Case studies in disease II: Cholera 10. Case studies in disease III: Malaria 11. Case studies in disease IV: HIV 12. Principles of laboratory diagnosis of infectious diseases Coursework Prepare a poster on one of the following topics: Evolution of the in²uenza virus Epidemiology of SARS Antibiotic-resistance in pathogenic bacteria Detailed guidelines and instructions are on the course website. Deadline for submission: 17th April 2008
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2 On-line support for teaching • For Dr Pointing’s lecture notes: – www. extremophiles .net – Login using: • Username: student • Password: microbiology – After login click ‘downloads’ icon on main menu to see ±les available for download Examination • A one-hour multiple choice examination containing 60 questions –(70% of overall grade) • An assessment of your poster –(30% of overall grade) So now lets have the ±rst lecture Early ideas about disease • We know today that disease is caused as the result of microbial infection to the body • But of course this was not so obvious in ancient times before microbes had been discovered !
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3 A brief history of early advances in medicine • Early ‘treatment’ of disease was based largely on the supernatural model – Treatments generally involved lots of prayer and sacriFce ! • The Greek-Roman empires created ways of thinking that resulted in major advances in anatomy, physiology and therapeutics – The four humours theory was also developed, and this in±uenced medicine for centuries to come – Hippocrates (460-377BC), devotee of the Greek God of Healing Adelphius , described the 4 humours in the body (later developed by Aristotle and others) as a way to explain and treat disease – Galen (130-210AD), another Greek became
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BIOL0131_L1 handout_2009 - Basic Medical Microbiology...

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