Disc_3-Allison

Disc_3-Allison - 3. How did he test this hypothesis? (Pay...

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Biology 108 Discussion #3 Case Study: Sickle-Cell Anemia Questions to consider while reading Allison, “Polymorphism and natural selection in human populations”. 1. Why was the relatively high frequency of sickle-cell trait in parts of Africa unexpected? 2. Allison linked the distribution of Hb β S with falciparum malaria. What hypothesis did he propose as a result of this observation?
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Unformatted text preview: 3. How did he test this hypothesis? (Pay particular attention to Tables 1-3, and Figures 1-2) 4. What other indirect support does Allison provide for his hypothesis? 5. Background information for pp. 141-143: G-6-PD deficiency, and the mutant hemoglobin alleles Hb C and Hb T (causing -thalassemia) all confer some resistance to malaria....
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Disc_3-Allison - 3. How did he test this hypothesis? (Pay...

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