WZ handout13

WZ handout13 - Weihao Zheng BIPN 100 whzheng@ucsd.edu...

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Weihao Zheng BIPN 100 whzheng@ucsd.edu Handout #1 Membrane Transport and Electrophysiology I. NEUROPHYSIOLOGY a. Anatomy i. Neuron – the functional unit of the nerve ii. Dendrites – the main inflow tract iii. Soma – cell body iv. Hillock – where action potentials (AP) generate v. Axon – main outflow tract vi. Axon terminals – branch out and contact different cells aka other neurons or muscle fibers II. MEMBRANE TRANSPORT a. Ion Channels Channel Type What’s unique about it? Give an Example leak ligand-gated voltage-gated mechanically-gated b. Transporters i. More selective than ion channels and usually slower ii. Undergo a conformational change of protein iii. At no moment is intracellular fluid is connected directly with extracellular fluid. c. Types of transport mechanism 1
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Weihao Zheng BIPN 100 whzheng@ucsd.edu Passive / Active Transport Mechanism Examples Ion Channels Uniport Ion Pumps Symports/Antiports ***70% of ATP is used in active transport in neurons III. ELECTROPHYSIOLOGY a. Nernst Equation = E ion = i. Equilibrium potential = The electrical driving force of a single ion ii. What happens when the membrane is permeable to a divalent ion? 30.5 * ….
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WZ handout13 - Weihao Zheng BIPN 100 whzheng@ucsd.edu...

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