Lec1 - What is biochemistry? Chemistry of life Structures...

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What is biochemistry? Chemistry of life Structures of the molecules of life? How do molecules interact? How are biological molecules made and degraded? How is energy conserved and used? How are biological molecules organized, coordinated and regulated? How is genetic information stored and expressed?
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Why are we asking those questions? Academic interest Solving medical problems Economic purposes
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Tools Physics 3-D structures Chemistry Synthesis, purification, modification Molecular genetics Clone and modify genes Cell biology
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Chapter 1 Life 1. Origin of life 2. Cellular architecture 3. Evolution 4. Thermodynamics
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What is the composition of life?
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Wet weight 70% H 2 O Dry weight C, O, H, N 87% Ca, P, K, S 10% Cl, Na, Mg 2% Trace elements
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How old is life? 3400 million years old
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Where did life come from? Chemical evolution
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Organic molecules Replicating molecules Simple organisms Prebiotic world
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No way to study the original process Can we recreate what happened? Simple building blocks
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This note was uploaded on 10/28/2010 for the course CHEM 114A taught by Professor Viadhiu during the Fall '08 term at UCSD.

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Lec1 - What is biochemistry? Chemistry of life Structures...

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