Lec4 - DNA Complementary Strands DNA Double helix Stands...

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NUCLEOTIDES
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Bases are derivatives of purine or pyrimidine
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Adenosine derivatives perform various functions Building blocks for DNA Building blocks for RNA Nucleotide function
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Adenosine acts as an autocoid Regulates a variety of processes Vessel dilation, smooth muscle contraction, hart rate Sleep During wakefulness adenosine levels in the brain rise causing sleepiness
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ATP carries energy FADH 2 and NADH carry electrons to the electron-transport chain NADPH carries electrons to sites of biosynthesis CoA carries activated acetyl and acyl groups
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ATP acts as a carrier of energy
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Bases are derivatives of purine or pyrimidine
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Deoxyribonucleotides
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Rosalind Franklin’s data: DNA is a helix
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Tautomeric forms of Bases
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DNA double helix
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Left and right handed helices
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Base-pairing
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Tautomeric forms of Bases
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Unformatted text preview: DNA Complementary Strands DNA Double helix Stands run anti-parallel Bases are planar and are in the center of the helix Major and a minor groove Bases on one strand base-pair with complimentary bases on the other strand Sugar is deoxyribose Formation of a stem-loop structure Differences between DNA and RNA Double stranded Contains deoxy-ribose Contains A, T, G, C Encodes genetic information Single stranded Contains ribose Contains A, U, G, C Is involved in expression of genetic information DNA Carries Genetic Material Transformed pneumococci DNA can be replicated reliably Transcription & Translation Central Dogma of Molecular Biology Translation: Synthesis of protein from messenger RNA...
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This note was uploaded on 10/28/2010 for the course CHEM 114A taught by Professor Viadhiu during the Fall '08 term at UCSD.

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Lec4 - DNA Complementary Strands DNA Double helix Stands...

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