Lec7 - General Structure of an Amino Acid A Zwitterionic...

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General Structure of an α - Amino Acid
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A Zwitterionic Amino Acid At neutral pH, the amino and carboxylic acid groups are ionized
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Condensation of Two Amino Acids
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Disulfide-Bonded Cysteine Residues
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Non-Polar Amino Acids
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Non-Polar Amino Acids
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Non-Polar Amino Acids
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Uncharged Polar Amino Acids
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Uncharged Polar Amino Acids
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Charged Amino Acids
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Amino Acids with Surface presentation
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Non-polar amino acids Center of globular proteins Transmembrane domains Non-polar interactions Responsible for protein aggregation
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Uncharged polar amino acids Participate in hydrogen bonding Stabilizing protein structure Protein-protein interactions Enzyme substrate interactions Undergo modification
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Charged amino acids Present on the surface of proteins Ionic interactions other protein membrane Histidine - pK R is 6.04 10% is positively charged (pH 7.0) pKa can be affected by the local environment Can donate or absorb protons during catalysis
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Titration of Glycine
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Lec7 - General Structure of an Amino Acid A Zwitterionic...

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