Lec18 - LIPID BILAYER Bilayer Formation Micelle Liposome...

Info iconThis preview shows pages 1–10. Sign up to view the full content.

View Full Document Right Arrow Icon
LIPID BILAYER Bilayer Formation Micelle Liposome Mobility of Lipid in the Bilayer Enzymes Temperature dependence
Background image of page 1

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
Amphiphilic molecules form micelles or bilayers Amphiphilic molecules with a single long hydrocarbon chain form micelles
Background image of page 2
Amphiphilic molecules with two long hydrocarbon chains like to form bilayers
Background image of page 3

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
Lipid bilayers are ~ 60Å thick 15Å 30Å 15Å Central 30A is hydrophobic Water can penetrate 15A into the bilayer from both sides
Background image of page 4
Membranes are Fluid Lipids diffuse both laterally and across the bilayer Lateral diffusion is fast Transverse diffusion is slow
Background image of page 5

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
A computer models of the lipid bilayer
Background image of page 6
Cholesterol provides rigidity Unsaturated fatty acids promote fluidity -Heterogeneity in the length of hydrocarbon chain and bond unsaturation are mostly responsible for membrane fluidity Membrane undergoes phage transition -Membrane becomes gel-like below certain temperature which is called the Transition Temperature Above the transition Temperature lipids are in Liquid Crystal form Bilayer Properties
Background image of page 7

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
BIOLOGICAL MEMBRANES
Background image of page 8
Membranes separate inside from outside Divide the cell into compartments Biological membranes contain both proteins and lipids Plasma membrane; ~ 50% ratio Mitochondria ~75% protein Nerve axon ~25% protein
Background image of page 9

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
Image of page 10
This is the end of the preview. Sign up to access the rest of the document.

Page1 / 36

Lec18 - LIPID BILAYER Bilayer Formation Micelle Liposome...

This preview shows document pages 1 - 10. Sign up to view the full document.

View Full Document Right Arrow Icon
Ask a homework question - tutors are online