lec1 - Biochemical Energetics and Metabolism(Chem/Biochem...

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1 Biochemical Energetics and Metabolism (Chem/Biochem 114B) Professor Wei Wang [email protected]
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2 Website Course Details http://webct.ucsd.edu Office Hours Mon. & Wed., 12-1 PM, 4254 Urey Hall Exams Mid-term (in class, 30%), Fri., Feb. 8 Final (50%) ,Mon., Mar. 17 NO make up exams Problem sets (20%) due in each Wed. class late homework NOT accepted TAs check your attempt Gone over in sections TA’s Amy Davenport, John Ewalt, Kwan-I Wu
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3 Outline Text — Fundamentals of Biochemistry (2nd Edition). Voet, Voet, Pratt. Wiley & Sons, Inc., New York. 2006. Topic Time Carbohydrates Weeks 1-3 Citric Acid Cycle, Oxidative Phosphorylation, Photosynthesis Weeks 3-5 Lipids Weeks 6-7 Proteins Weeks 7-8 Nucleotides Week 9 Metabolic network and disease Weeks 9-10 Midterm (30%) Final (50%) • Problems from Voet, Voet, Pratt — gone over in section the following week
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4 Syllabus
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5 How to take notes Lectures are guided tour of detailed information in Voet/Voet/Pratt Overall important points from Lecture Details from Voet/Voet/Pratt readings Lecture powerpoints available night before lecture Coming soon, list of key terms/concepts and molecules you should know
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6 Outline Why study metabolism? Overall principle of metabolism High-energy compounds Oxidation-reduction reactions
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7 Why study metabolism? ¾ Metabolism is essential to life ¾ Metabolic Disorders lead to diseases Obesity and diabetes Aging (caloric restriction)
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8 Prevalence of Obesity among Prevalence of Obesity among U.S. Adults, BRFSS, 1985 U.S. Adults, BRFSS, 1985 <10% <10% 10 10 -15% 15% >15%
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9 <10% <10% 10 10 -15% 15% >15% Prevalence of Obesity among Prevalence of Obesity among U.S. Adults, BRFSS, 1998 U.S. Adults, BRFSS, 1998
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10 1.1 million people died of diabetes in 2005 (WHO) 50% increase expected over next 10 years Childhood obesity ‘Metabolic syndrome’ Cardiovascular disease ± Insulin resistance ± Hypertension Growing Plague of Obesity and type II diabetes
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11 Outline Why study metabolism?
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This note was uploaded on 10/30/2010 for the course CHEM 114B taught by Professor Wang during the Winter '09 term at UCSD.

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lec1 - Biochemical Energetics and Metabolism(Chem/Biochem...

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