lec26 - Lecture 26 Hormone control of Metabolism...

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1 Lecture 26 Hormone control of Metabolism (continued)
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2 Insulin Resistance Normal concentrations of insulin produce subnormal biological response Common in ± Obesity ± Type-2 diabetes ± Metabolic syndrome ± Polycystic ovarian disease ± Pregnancy ± Puberty
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3 Increased risk of coronary heart disease and other diseases related to plaque buildups in artery walls (e.g., stroke and peripheral vascular disease) and type 2 diabetes 50 million Americans Risk factors ± Abdominal obesity ± Elevated blood pressure ± Insulin resistance or glucose intolerance ± …… Metabolic Disorder
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4 Three or more ± Elevated waist circumference: Men — Equal to or greater than 40 inches / Women — Equal to or greater than 35 inches ± Elevated triglycerides — Equal to or greater than 150 mg/dL ± Reduced HDL (“good”) cholesterol: Men — Less than 40 mg/dL Women — Less than 50 mg/dL ± Elevated blood pressure: Equal to or greater than 130/85 mm Hg ± Elevated fasting glucose: Equal to or greater than 100 mg/dL Metabolic Disorder
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5 Insulin Response
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This note was uploaded on 10/30/2010 for the course CHEM 114B taught by Professor Wang during the Winter '09 term at UCSD.

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lec26 - Lecture 26 Hormone control of Metabolism...

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