Lecture1

Lecture1 - Welcome to chem114C: Biosynthesis of...

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1 Welcome to chem114C: Biosynthesis of Macromolecules Alexander Hoffmann Signaling Systems Laboratory Chemistry and Biochemistry Natural Science Building, Room 3328 [email protected]
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2 Course Objective : The biochemistry of storage, inheritance, repair, transmission, and expression of Genetic Information “The Central Dogma of Molecular Biology” Experiments that revealed what we know today. Experimental techniques that are being used to extend our current knowledge. Fundamentals of Biochemistry by Voet, Voet & Pratt 2nd Edition
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3 Maximize what you get out of this class: - Be sure you have mastered chapters 3, 4, 5, 6 - Prepare by reading ahead - Take notes in lecture - Participate in lecture - Attend Discussion Sections - Come to office hours - Work in study groups
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4 Exams and Grading: Textbook is your guide: chapters 23-27 - but not all the details shown in the book are required: come to lectures or look at slides to determine what details are required. - some additional material will be presented in Lecture (about 10%) - Exams will be about all the material covered in Lecture and Sections Midterm I (25%) (Thursday of 4th week): 4/23 Midterm II (25%) (Tuesday of 7th week): 5/20 Final (50%) (Thursday 6/12, Location TBA) Midterms are returned one week after. Regrade requests are accepted within 24 hrs when accompanied with a written note. Grading will be on the curve. Academic Integrity: http://www- senate.ucsd.edu/manual/appendices/app2.htm#AP14
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5 Lecture chapter Section Tue 4/1 DNA chemistry and structure 3; 23.1 Thu 4/3 DNA/RNA chemistry and structure 23.1-3 Tue 4/8 DNA-protein interactions 23.3-5 DNA/RNA chemistry restriction enzymes, PCR, electrophoresis Thu 4/10 DNA replication I 24.1-2 Tue 4/15 DNA replication II DNA, interactions replication Thu 4/17 DNA damage 24.3-4 Tue 4/22 DNA repair, recombination 24.4-6 Review Practice Exam Thu 4/23 Midterm I: in class room Tue 4/29 Transcription: the prokaryotic machine 25.1 Review of Midterm I Thu 5/1 Transcription: the eukaryotic machine 25.2 0 Tue 5/6 RNA splicing and processing 25.3 transcription splicing 1 Thu 5/8 Translation: the Code and tRNAs 26.1-2 2 Tue 5/13 Translation: the ribosome protein
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This note was uploaded on 10/30/2010 for the course CHEM 114C taught by Professor Alexanderhoffmann during the Spring '08 term at UCSD.

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Lecture1 - Welcome to chem114C: Biosynthesis of...

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