This preview shows page 1. Sign up to view the full content.
Unformatted text preview: containing both S-strain and R-strain cells. The purified extract contained Griffith's "transforming principle". Through biochemical testing, they showed it to be deoxyribonucleic acid (DNA). 1. Removing the protein from the extract of the S strain with organic solvents still allows transformation 2. Digesting the extract with enzymes that destroy protein still allows transformation 3. Treating the extract with ribonuclease (which degrades RNA) still allows transformation 4. Treating the extract with DNase (which degrades DNA) destroys the ability of the extract to transform cells Nucleotide is the sugar, base, & phosphate Nucleoside is the base & sugar w/o phosphate Purines are attached at their N9 position to the 1’ carbon atom of sugar Pyrimidines are attached at their N1 position to the 1’ carbon atom of sugar...
View Full Document
This note was uploaded on 10/30/2010 for the course CHEM 114C taught by Professor Alexanderhoffmann during the Spring '08 term at UCSD.
- Spring '08