Week 3 Exb 110 2010 color

Week 3 Exb 110 2010 color - EXERCISEMETABOLISM EXB110...

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EXERCISE METABOLISM EXB 110 Carbohydrate Metabolism
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High Carbohydrate food Food Serving Size Carbohydrates (grams) per serving Fruits apricot, nectar 1 cup 36 banana, sliced 1 cup 35 blueberries, raw 1 cup 20 dates, whole, pitted 10 61 figs, dried 10 122 grapefruit juice 1 cup 72
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#E n z y m e 1H e x o k i n a s e 2 Phosphogluco isomerase 3 Phosphofructokinase 4 Aldolase 5 Triose phos. Isomerase 6G 3 PDH 7 Phosphoglycerate kinase 8 Phosphoglycerate mutase 9E n o l a s e 10 Pyruvate kinase 1 1 2 3 10 9 8 7 6 5 4
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Glycolysis • Is metabolic pathway by which glucose is converted into 2 pyruvates • Does not require oxygen • Overall net equation is: – glucose + 2NAD + 2ADP + 2P i 2 pyruvates + 2NADH + 2 ATP
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Glycolysis • Glycolysis is exergonic - produces net of 2ATPs and 2NADHs • However, glucose must be activated with 2ATPs (phosphorylation ) before energy can be obtained – Phosphorylation traps glucose inside cell
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Glycolysis • In glycolysis 2ATPs are added and 4 are produced for a net gain of 2 ATP
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Glycolysis
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Glycolysis Glycolysis What is glycolysis? Ten step metabolic pathway to convert glucose into two molecules of pyruvate and two molecules each of NADH and ATP. All carbohydrates to be catabolized must enter the glycolytic pathway. Glycolysis is central in generating both energy and metabolic intermediaries.
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Pyruvate Pyruvate can be further processed: a) anaerobically to lactate lactate in muscle and in certain micro organisms or b) anaerobically to ethanol ethanol (fermentation) or c) aerobically to CO 2 and H 2 O via the citric acid cycle.
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‐‐ Alcohol fermentation and anaerobic glycolysis (lactate) are not efficient energy providers since this glycolytic pathway yields little ATP. ‐‐ Aerobic processing of pyruvate through the citric acid cycle and respiration gives a more complete oxidation and a much higher ATP yield. Glycolysis provides pyruvate, a precursor for respiration, the utilization of reactions with oxygen.
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Carbohydrate Metabolism Overview glycogen pentose GLUCOSE other sugars pyruvate lactate acetyl CoA TCA cycle ATP
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Carbohydrate Metabolism Overview glycogen pentose GLUCOSE other sugars pyruvate lactate acetyl CoA TCA cycle ATP
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Glycolysis: General Functions Provide ATP energy Generate intermediates for other pathways
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This note was uploaded on 11/02/2010 for the course EXB Exb 110 taught by Professor Aldringomes during the Spring '10 term at UC Davis.

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Week 3 Exb 110 2010 color - EXERCISEMETABOLISM EXB110...

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