Lecture11._Endocrine_System

Lecture11._Endocrine_System - Endocrine System...

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Endocrine System
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Long-Distance Regulators Animal hormones are chemical signals that are secreted into the circulatory system and communicate regulatory messages within the body Hormones reach all parts of the body, but only target cells are equipped to respond
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The endocrine and nervous systems function together in maintaining homeostasis, development, and reproduction The nervous system conveys high-speed electrical signals along specialized cells called neurons The endocrine system secretes hormones that coordinate slower but longer-acting responses
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Chemical Signals Hormones convey information via the bloodstream to target cells throughout the body
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Local regulators Transmit information to target cells near the secreting cells Paracrine Autocrine
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Synaptic signaling and neurohormones
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Pheromones Carry messages to different individuals of a species
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Hormones Three major classes of molecules function as hormones in vertebrates: Proteins and peptides Amines derived from amino acids Steroids Most protein/peptides and amine hormones are water soluble, unlike steroid hormones
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Cellular Response Pathway for Water-Soluble Hormones The receptors for most water-soluble hormones are embedded in the plasma membrane, projecting outward from the cell surface Binding of a hormone to its receptor initiates a signal transduction pathway leading to responses in the cytoplasm or a change in gene expression
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This note was uploaded on 11/02/2010 for the course CHEM 51LA 56555 taught by Professor Guan during the Spring '10 term at UC Irvine.

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Lecture11._Endocrine_System - Endocrine System...

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