LS03 - NPB 12 Lecture 3 Patient Spinal cord injury Polio...

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NPB 12 Lecture 3
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Patient Feel touch? Feel pain? Voluntary Reflexes? movement? Spinal cord injury No No No Yes Polio Yes Yes No No Leprosy No No Yes No Cut nerve No No No No
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Dorsal horn Ventral horn (Dorsal root) (Ventral root) Dorsal Root Ganglion
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Gray matter: Cell bodies White matter: Axon tracks Gray matter: Cell bodies White matter: Axon tracks
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LEG LEG Retrograde LEG LEG
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LEG LEG Anterograde LEG LEG
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LEG LEG Anterograde LEG LEG Axons to muscles in legs
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Anterograde LEG LEG LEG LEG Axons in skin, and a few in the joints
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A B C
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Motor Sensory (touch)
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Feel touch? Feel pain? Voluntary Reflexes? movement? Spinal cord injury No No No Yes Polio Yes Yes No No Leprosy No No Yes No Cut nerve No No No No Information to and from the brain is gone, the reflex is still there. The motor (ventral) neurons are gone: no motor movement but the sensory information is fine The sensory (dorsal) neurons are gone: no sensation to start the reflex, but the communication from the brain to the ventral motor neurons is fine so they can move voluntarily. The axons of both the dorsal sensory and ventral motor cells are cut,
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This note was uploaded on 11/08/2010 for the course NPB 72121 taught by Professor Hwai-jongcheng during the Fall '10 term at UC Davis.

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LS03 - NPB 12 Lecture 3 Patient Spinal cord injury Polio...

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