Problem Set 4 KEY

# Problem Set 4 KEY - Problem Set 5 Page 1 of 3 Problem Set 4...

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Problem Set 4 1) Draw the following structures: 2) Membrane lipids from 4.74*10 9 erythrocytes form a monolayer of 0.89 m 2 in water. The surface area of an average erythrocyte is ~ 100 μ m 2 . Show that the membrane is a bilayer. The surface are of this many erythrocytes works out to: This is approximately ½ the measured area, implying that the membrane of each erythrocyte must contain two layers of lipid. 3) How many moles of K + will diffuse across the erythrocyte membrane in one minute under the following conditions: [K + ] in = 100 mM [K + ] out = 15 mM Surface Area of erythrocyte: 100 μ m 2 = 100*10 -12 m 2 Permeability P of K + = 2.4*10 -10 cm-sec -1 Put everything in terms of centimeters (i.e. convert mols/liter to mols/cm 3 , m 2 to cm 2 , etc.) 4) If the erythrocyte volume is 100 μ m 3 , what percent of the internal K + willl leak out in 1 minute? cis -9-docenoic acid 18:1c 11 Saturated FA w/ Tm < 30oC (any saturated FA with 9 or fewer carbons) 9 12 2 1 2 4.74 10 100 10 0.474

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Problem Set 4 KEY - Problem Set 5 Page 1 of 3 Problem Set 4...

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