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Unformatted text preview: P) with a negative G rxn . ( B ) The corresponding enzyme-catalyzed reaction in which S binds loosely to the enzyme. ( C ) The corresponding enzyme catalyzed reaction in which S binds very tightly to the enzyme. A B C Indicate G in each case ( A-C ). For B and C , are they larger or smaller than for A ? (Answer both) Do you expect reaction B and C will be slower or faster than A ? (Answer both) 5. Haloalkane dehalogenase is a detoxification enzyme that catalyzes the reaction below. This enzyme has an aspartate residue that is essential for catalysis. Propose a mechanism for the enzyme-catalyzed reaction be sure to include a role for the aspartate residue . G Reaction Progress G Reaction Progress G Reaction Progress Cl Cl OH Cl + H + + Cl-+ H 2 O Haloalkane Dehalogenase...
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