MWF_29 - Organic Lecture Series CH 310/318 M Textbook...

Info iconThis preview shows pages 1–4. Sign up to view the full content.

View Full Document Right Arrow Icon
Organic Lecture Series 1 CH 310/318 M LECTURE 29 Textbook Assignment: Chapter 9- Nucleophilic Substitution Today’s Topics: The Sn1 and Sn2 Reactions The Sn1 and Sn2 Reactions Notice & Announcements: Office Moved to WEL 4.242 Location for office hrs TBA Organic Lecture Series 2 Nucleophilic Nucleophilic Substitution Substitution and and β β - - Elimination Elimination Chapter 9 Chapter 9
Background image of page 1

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
Organic Lecture Series 3 • At one extreme, the two processes take place simultaneously; designated S N 2. –S = substitution –N = nucleophilic –2 = bimolecular (two species are involved in the rate- determining step) Mechanisms Mechanisms Organic Lecture Series 4 – Both reactants are involved in the transition state of the rate-determining step. CB r H H H HO: - + C H H H HO Br δ - δ - Transition state with simultaneous bond breaking and bond forming C H H H HO + Br : :: : : Mechanisms S Mechanisms S N 2
Background image of page 2
Organic Lecture Series 5 • An energy diagram for an S N 2 reaction. There is one transition state and no reactive intermediate. Mechanisms S Mechanisms S N 2 Organic Lecture Series 6 • Bond breaking between carbon and the leaving group is entirely completed before bond forming with the nucleophile begins. • This mechanism is designated S N 1 where – S = substitution – N = nucleophilic – 1 = unimolecular (only one species is involved in the rate-determining step) Mechanisms S Mechanisms S N 1
Background image of page 3

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
Image of page 4
This is the end of the preview. Sign up to access the rest of the document.

Page1 / 10

MWF_29 - Organic Lecture Series CH 310/318 M Textbook...

This preview shows document pages 1 - 4. Sign up to view the full document.

View Full Document Right Arrow Icon
Ask a homework question - tutors are online