15 Sex, Drugs, and Rock and Roll

15 Sex, Drugs, and Rock and Roll - Sex, Drugs, and Rock...

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Remember that sexual arousal depends on stimuli from all five senses. Recall that sexual arousal requires adequate arterial inflow. Acetylcholine and nitric oxide are needed for this. Hormones are involved, too. We all need testosterone for sexual arousal. But increased estrogen (in males and females), or an increased estrogen:testosterone proportion decreases libido. High prolactin levels decrease libido directly. Drugs that block dopamine activity increase prolactin and thereby decrease libido. Neurotransmitters: Dopamine is a key neurotransmitter in the brain’s “pleasure center.” Increasing dopaminergic activity increases pleasure; decreasing dopaminergic activity reduces pleasure. Serotonin can diminish the release of dopamine, with unhappy consequences as far as sex goes. Substances with anticholinergic properties (they block acetylcholine); selective serotonin reuptake inhibitors (SSRI’s); dopamine-blocking drugs (eg., to treat psychotic symptoms) – these may mess with nitric oxide synthesis. Thereby messing with your arousal. Serotonergic antidepressants are the most common cause of delayed ejaculation and anorgasmia. SSRI’s (selective serotonin reuptake inhibitors), include Zoloft, Prozac, Paxil, Luvox, Lexipro, Decrease libido, inhibit orgasm – perhaps by inhibiting dopamine. (They may prove helpful with premature ejaculation.) Antidepressants such as Welbutrin can enhance dopamine activity. L-DOPA (Wellbutrin, etc.): Increased DOPAMINE can raise sex drive, but can also trigger PRIAPISM (a painful and potentially highly problematic erection that won't go away, the treatment of which may put an end to all erections).
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Aphrodisiac : any drug or other agent that is sexually arousing or increases sexual desire. (From
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This note was uploaded on 11/08/2010 for the course EDP 363 taught by Professor Brownstein during the Spring '08 term at University of Texas at Austin.

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15 Sex, Drugs, and Rock and Roll - Sex, Drugs, and Rock...

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