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OB_Flagyl (metronidazole)

OB_Flagyl (metronidazole) - Flagyl(metronidazole Routine...

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Flagyl (metronidazole) Routine use: Treatment of anaerobic infections Safe dose & range: PO (Adults): Anaerobic infections --7.5 mg/kg q 6 hr (not to exceed 4 g/day). Trichomoniasis --250 mg q 8 hr for 7 days or single 2-g dose or 1 g bid for 1 day. Amebiasis --500-750 mg q 8 hr for 5-10 days. H. pylori --250 mg 4 times daily or 500 mg twice daily for 1-2 wk (with other agents). Bacterial vaginoses --750 mg once daily as ER tablets for 7 days. Antibiotic associated pseudomembranous colitis --250-500 mg 3-4 times/day for 10-14 days. Vag (Adults): Bacterial vaginosis --One applicatorful (5 g) 2 times daily for 5 days. Classification, Action & Indication: C- Therapeutic: anti-infectives, antiprotozoals, antiulcer agents A- Disrupts DNA and protein synthesis in susceptible organisms. Therapeutic Effects: Bactericidal, trichomonacidal, or amebicidal action. Spectrum: Most notable for activity against anaerobic bacteria, including: Bacteroides , Clostridium . In addition, is active against: Trichomonas vaginalis , Entamoeba histolytica , Giardia lamblia , H. pylori , Clostridium difficile . I- PO IV: Treatment of the following anaerobic infections: Intra-abdominal infections (may be used with a cephalosporin), Gynecologic infections, Skin and skin structure infections, Lower respiratory tract infections, Bone and joint infections, CNS infections, Septicemia, Endocarditis. IV: Perioperative prophylactic agent in colorectal surgery.
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