Management of hypertension.
100 mg twice daily initially, may be increased by 100 mg twice daily q 2-3 days as
needed (usual range 400-800 mg/day in 2-3 divided doses; doses up to 1.2-2.4 g/day have been used).
20 mg (0.25 mg/kg) initially, additional doses of 40-80 mg may be given q 10 min as
needed (not to exceed 300 mg total dose)
2 mg/min infusion (range 50-300 mg total dose required).
A- Decreased blood pressure.
Major side effects:
, anxiety, depression, dizziness, drowsiness, insomnia, memory loss, mental
status changes, nightmares.
blurred vision, dry eyes, nasal stuffiness.
, orthostatic hypotension
constipation, diarrhea, nausea.
, decreased libido.
arthralgia, back pain, muscle cramps.
drug-induced lupus syndrome.
Monitor blood pressure and pulse frequently during dose adjustment and periodically during
therapy. Assess for orthostatic hypotension when assisting patient up from supine position.