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MCB124Lecture1 - MCB 124 Molecular Structure and Function...

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MCB 124 MCB 124 Molecular Structure and Function Part 1: Structure TR 4:10-6:00pm: 198 YOUNG Professor Nigel D. Browning ( [email protected] ) Office Hours Tuesday 10:00-11:00am and Thursday, 2:00-3:00 PM or by appointment 2010 Kemper, tel: 754-5358
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MCB 124 Grades for Part 1 (50% of total) 3 graded quizzes (15%) midterm exam (35%) Practice questions and solutions will be posted each week
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MCB 124 What do we mean by Structure? - Need to define a labeling scheme that allows us to uniquely define a particular molecule, protein, metal etc - Usually aim to find the smallest unique building block of the structure to define it - Basic principle of all the sciences is that if you can define the structure in this way, you can predict function - Used to design everything from the fastest computers to the newest drugs How do we start?……with physics!
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MCB 124 “God does not play dice.” – Albert Einstein What Physics do we need? Quantum Mechanics The Uncertainty Principle Wave-Particle Duality Schrodinger Equation Angular Momentum and Spin Pauli Exclusion Principle
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MCB 124 The Photoelectric Effect one of the first demonstrations of quantum mechanics http://mc2.gulf-pixels.com Light is composed of discrete “quanta” of energy that interact with electrons Albert Einstein – Nobel Prize for Physics (1921)
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MCB 124 Basic Building Block is an Atom - from the greek atomos meaning indivisible Most Important discovery: “Everything is made of atoms” – Richard Feynman reich-chemistry.wikispaces.com J. J. Thomson’s discovery of the electron in 1897 – “cathode rays” – led to the “plum pudding model”
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MCB 124 The Rutherford Atom Experiments by Geiger and Marsden led to the discovery of the nucleus http://www.daviddarling.info/encyclopedia “It was quite the most incredible event that has ever happened to me in my life. It
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