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Unformatted text preview: Question 1 • Metabolic- differentiating based on production of hormones: androgens, males, or estrogens, females, from endocrine glands. • Chromosomal- differentiating males and females based on presence of XX for female and XY for male chromosomes. • Genetic- SRY or no SRY gene • Gonadal- differentiating males and females based on gonadal tissue being present, i.e. having testes or ovaries • Phenotypic- differentiating males and females based on external genetalia, penis vs vagina Intersexuals happen 1) when a translocation of SRY gene to an X chromosome makes a chromosomal XX male. 2) Mutation in androgen receptor causing complete androgen insensitivity, a child with XY will have undescended testes and develop female genitalia. Do you think there is a continuum between the two sexes? Question 2 • Gene therapy o Use of genes to cure diseases, replacing mutant alleles with functional ones....
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This document was uploaded on 11/09/2010.
- Spring '07