Lecture16 - Summary 1. 2. 3. 4. 5. 6. Cell cycle,...

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Summary 1. Cell cycle, cell-cycle control system; 2. Cell division, mitosis, cytokinesis 3. Mitotic spindle, contractile ring 4. Programmed cell death, caspases; 5. Cell cycle and cell death are regulated; 6. Cancer is caused by uncontrolled proliferation of cells
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Chapter 16 Cell Junctions, Cell Adhesion, and the Extracellular Matrix Cells as structural and functional units of multicellular organism Cells are very “social”
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I- Two major types of tissues II- Study of the junctions III- The ECM
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Extracellular matrix: a complex network of proteins and polysaccharide chains that are secreted by cells 1- Connective tissues: lots of ECM and cells are more sparse Two distinct type of tissues 2- Epithelial tissues: cells are directly attached to each other, scant ECM (basal lamina)
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Rich in ECM Cell junctions to adjacent cells or basal lamina A cross-sectional view of part of the wall of the intestine
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The Cell junctions 1. Anchoring junctions --mechanically attach cells and their cytoskeleton to their neighbors or to the extracellular matrix; 2. Occluding junctions --seal cells together, prevent even small molecules from leaking from one side of the sheet to the other; 1. Channel-forming junctions --create passageways linking the cytoplasm of adjacent cells; 4. Signal-relaying junctions --mediate the passage of chemical or electrical signals from one interacting cell to its partner
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Lecture16 - Summary 1. 2. 3. 4. 5. 6. Cell cycle,...

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