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Week1 Section Notes

Week1 Section Notes - ’ I ‘ Le time 2 flcxzm...

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Unformatted text preview: ’. I.) ‘ Le time 2 flcxzm ogong‘mg, — genomes are ccmplEfele seq/What. -. WM S‘Nda 1mm? 1”give us Cm flea QbSUr q\\ similqr organisms. unce gene; are conserved» — SNdj hqmfi'fl dixBQSB, \ecs uhefivcwl My: brawn; . umceuumr - Exch " far www.mcxr gene’ncs. « Mulh cmNmr --m<m5€ - mopcumv evc\u’flcm-- ~zebraf‘fih develgpment (\rcgszHM - development _ generic resewch- Dr) . - Lamont. «Us ‘ cm1 c9.\\ Thm farm The bcdj of cm orgum'sm.. 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TL 5 ‘ ‘ — Nudecw chrcmos'cmei CW9. chromofir‘ 7 , - m \meersa’ , 1w huve >0 “m fiverm‘mc‘fl “nfk‘C‘S ‘“ Deans cm a 3mm} *— ,. nqgleofome .- £15m mp'zrmfi'} 'u'r'wx Mm m U Arm .13 er I’l’éj/ In Chrommtm. --". v—er ON P ‘3 \ {Manges Z " ., ~“.,‘Om rMLku e —@_/ ijm { mH' der' ‘OUU’V EDNH Eguence; regw’red fay gbonYiofcm€1 2‘. Ymcmeref «mgme ends cf DNR 30f rephcared — Prevent 131%;le 4 w romcgomei flcCldQnmllj iormlc, L’enh’cmer a kineTCrvthe Lmrou ad Ct‘fl*'r:r¥Ylerg hem Scpiu'ffl'? 33(1in V‘Qr cnrmxcgcmey / O’TIULh rhrmmfa’rmfi - anm cf Pep: fig [Eng Egg 2 3; - mgrcma mm --qef ‘m0r$\fi9d merhwom on, ®mhm ficeflflafim - Umctumu . 5 - ‘msrcne H1~- bmds nuc\€CSCXY\E +9 DNA m. '0 Code " mcmfimh‘ons gcj qg binding are; (Cr chrexns fimt are \nvclved with chrcrmufin grmcfure [can (\LhJCJe/'m.ochvc.fe N7} 9‘" QCQTIJXQHCTW a?“ or V’tZN‘;CYV“\b ‘kwml; H7>F17m83 ZPTCTQWS b‘nd‘ hereromrcmahr‘. is mowed DNR and. no W'm QCCufS‘ 11!th {my O'Qafl'z‘zah‘w’l / Gem/911 ixprggmd . , ~ ) - LOmemsh chrmnmome. - Wm mrcmwr‘uare'not’ expressed. L71!1*QV’PY‘20.§C LhTCmCSCme-S in omphvbmm .-Pci\{rene chrgmgyzme .— mkerphug—e CV‘ romcgcwe L7 mumme woes 0*: DNP 5mm wlc m «'ToSés - 1? mac ‘ 15/. d Dun .9 , .1 .7 - _ , . wreck-ox m“ W’We‘ mm _, ‘9 / DNPI m‘qher I€VQ\ cf' gene QXIWGSSM’L ‘fi 4 ,\‘.‘ _\ , \ .‘~‘..r ‘ ‘ r‘ .. PNF, ,{Iflexu m (hr Mw/qome Puff knew :Y‘xchme dficcfldenfl Nuuius is cm C‘rggn'iled S'Imgmre - N‘qdeclus - Deme SPQ‘r m nucfms ’ fxn= RIDCScmeS are Sym‘hesiled L7 mmfies rRNH’ -~ my“ Ewes (GEMS) an nudeus or prchf'erufing Lens. ,kfn‘P-NP ’ WNY'Q 3110?pr are QYOCQSSed, mqmred and recycled L1 prccess and gmmmalk} mchu’ rRNH > g-nRNPs ' fC-r mRNh Prccessmg /5P\“‘h9 fipnw premPNfl m nip—NP?- ’SPx-le-‘QS , am mrerwmmm‘. gmrmle (Mgr-WE Mmcmres bfwn chrC‘mahn . ~ thj hlxi comparfmeflralized ’W FDRNP mum- _, . . Lecmre 5 'wmer «fie-5+ abundant mOECule m qceu , 10'] c-F WQ-‘ghf " (’er bonds = uneven Charge dl‘gh‘{buh0n L"gme NSQ m H'bmd —fi—tmd§ ore nmccvalen’r {k {3 hde m RT. “quhmrche #ensmn $4 ESP. LH‘iPM 0? NWCWUWW WWYUCT‘WS - mmce up :hcpe Of macromolecme ’ Skrcnqesf I. Eled’rei‘mht thchon: (+3 6 cm cmmchms 2. Hydrogen Bond i W m Wm H atom inflame-TS with eluficnegufive mom. 9;. vunc\€YNQa\$ -\nremch0n MW” nemm/nonPohr - no Q‘ sharing. . «mum a, Heaven doud SmeQheWS fuckermg TC generate xlx‘gm CMrge‘ Ll. hqdrophobic force -ncnr0br SUVRJCQS are pushed 0fo of H'bmded H10 hefWor-‘r. CThermse mnpz'ym- mrfixcey wand mflerf‘ere WI fiyorowe H10 mnamchcrn; .‘4 organic mOIECUl65 - bungling [510(ng i $1qu "" mmmcchande 1. Farm acids *7 Fm] \npid/ membmne 3:. hmmo ficids ,_.~, Pmrem H. ”“035“(‘35 F" Nuueic. Pmd Cor ron DOS ad. None: smoncrganic rrlcleculm' can qlso fimcnvn as q monomer- . Sugars ' ceu enerqfi Smroa . Far Prods 995? W S‘W‘W “0256 - anew“ m , compn’se can membrane as phmphu‘sipd. . long mdrcphcbic Tun _endm<) ml CbeOQ\fl qfOJP warerorives QObr‘aAQ swucrure Ammg Hod — mmce up proTQiHS, can be pew or non pckw. * “mam b1 omxde bonds. am peph‘de bond: Nucwch‘des * mm=e UP DNR/RNPI r 'Fm qg 5mm Term comer: of chemucm org (MP7 mm mm; qunuhflg «mauve; , ext chMP qcnc adencsmemmormosphare CQH '10] Hit; '1 501‘ ther' ’h‘emimu "fi 0 . ‘ ‘- re - \ Cm]. C‘ m; G maurc mm kUWS ex: PY‘CW‘O. Rm mermorxj nomics ‘ TY‘E TQnC‘enC.\, FCY tYhnCJS ‘tG bacrme (jl'SCrdered — D! swam, = QnYrs-m . CQHS mus’r uhu‘ze when” 1:) mum—9r enTYO‘H and Heap orderoj 12532210 FCVJIHQ 9! ngcmre! [931235 I- "' PW RPM? (“mm 1' xx hehx, {55'196' ”named ‘01 H-bond (bled cm ~ prcvvde mechqmccn refinance m can, Rgmup mug,“ . 32' 3'0 ‘SfchrQ of prerem I vhehg g4 prrmcmre qre fclded mm 5mgmg’2n ‘1‘ mcncmer. chmer , refmmer. SUbunWS- «non CC‘VGIQOT- FLW“ 1‘”!ch 9mipxcf prcrem , m. all (gummy prm‘exyei Prcrem' PrCTEI-n 'Vll'eramonf L . LeCmi’Ql“ BQMCS MICYO fcc gj ‘ Resaiuncn \/§ Magmh COMO"I a: Deracfi‘ofi- . , . ~ - . N. W Demcfim— Tell :9 mfle'rhmcj IS mete (J Resoluficn- abs'tm, T0 t2“ 2 Dhj’eds apart. OO Hagmfimfim— size of cm .mage fiescumcxx 6: Hmfiad bx; maveIEmg‘m ‘9 Shcr’r Wm'elengrh ,DE‘H’QY resciufic'n. [nee verso. -- opn'cm diffrqc’nm games pocv reSmuh’m‘ - Challenges ' ‘QQSGth vfiampe \hrarafim ~ Nsnda Mcfive — 7a- D Veam‘rmch‘m, ‘uqm Mmcsccm -Lxmxmh"on is J‘Q’r a, WleEngfl’I Cf 'yl'SiAb\Q l‘qm— (OH ,um) =7 CFQPP‘}, O W o Bh‘gh’r fi‘md mom/non [\gh’f pqgsrgfhrwgn cell. Images drrecflfi v F‘nQS'e- canvas? - NUS dx‘flerem‘ densifiELY “runes qdmnmqe muff those Can shift when Wm cram TC) mew dep’rh. o Ngrmosb DWEQrQnml ~ DC -:69 surface OFCQH , Seq). mgmbrahe changhg v amp fie\d - ‘uurmnmffig “‘15 more Scu’rrered a} Pagan? mmqh amen/“FR; whcfi W9 See‘ "Norel shining grades confirms: F0: ens-4 wemng; pm' Pr HHS (any. 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