Bio 325-Genetics

Bio 325-Genetics - Chapter12 Definitions Cellfate,...

Info iconThis preview shows pages 1–3. Sign up to view the full content.

View Full Document Right Arrow Icon
Chapter 12 Developmental genetics Definitions Cell fate , what the cell or its descendants will become in the course of normal  development. Cell determination , the process of gradual commitment to a particular  developmental pathway from which the cells rarely depart. Cell potency , the ability of a cell to depart from its fate.  The ability of a cell to  produce other types of cells. A  totipotent  cell can produce any cell type in the  individual. Saturation mutagenesis  is used to produce mutations for every gene that  contributes to a process.  Know all material on this topic in the text. Pattern formation  in the  Drosophila  embryo. Morphogenesis  is the development of form. Pattern formation  is the development of a special organization in which the  tissues and organs are positioned properly. How are the cells that develop in the egg directed to become the correct  structures in the correct positions.   Review of  Drosophila  development The developing egg The cell that will become the egg ( oocyte ) is produced in the ovarian follicle. Nurse cells  (located at the end of the egg that will become the anterior end)can  transfer substances to the developing egg cell.  One such group of substances  are cytoplasmic determinants.
Background image of page 1

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
Cytoplasmic determinants  (eg. The mRNA from which transcription factors will  be made) are transcribed from the mother’s loci and transferred to the developing  egg cell by the nurse cells. These determinants are not distributed equally in the egg.  So they provide the  initial positional information in the egg. Development of the multinucleated stage When the egg is fertilized the zygote has a single nucleus. The nucleus divides by mitosis to produce many nuclei. Nuclei migrate to the periphery of the zygote. (Form a syncitium,  Syncytial  blastoderm stage ) pole cells have budded off at the posterior pole. Transcription of embryonic genome begins.
Background image of page 2
Image of page 3
This is the end of the preview. Sign up to access the rest of the document.

This note was uploaded on 11/11/2010 for the course BIO 325 taught by Professor Saxena during the Spring '08 term at University of Texas.

Page1 / 6

Bio 325-Genetics - Chapter12 Definitions Cellfate,...

This preview shows document pages 1 - 3. Sign up to view the full document.

View Full Document Right Arrow Icon
Ask a homework question - tutors are online