Ch 15 Notes - C15Mutation(DRAFT)...

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C15 Mutation (DRAFT) All page numbers are for your edition of the text. Read quickly   the relevant material only on pp 514-530. Mechanisms of gene mutations No problems assigned. You are only responsible for the text material that is on the pages  mentioned in these notes. Do Not memorize any other boldface terms that are not mentioned in the  notes. From Table 14-2 p 515. Know the following mutation types:  Transition Transversion Synonymous Missense Nonsense  Today all new alleles result from mutation of preexisting alleles. Forward mutation produces a new allele. Reverse mutation is a mutation back to the original allele. Mutations in germ-line can be transferred to progeny. Somatic mutations cannot. Mutation rates tend to be low in plants and animals, averaging one mutation in  every 100,000 genes per generation.  Spontaneous mutations vs Induced mutations p 518. Induced mutations, mutagens cause higher mutation frequency. Spontaneous mutations  include:
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Errors in DNA replication Role of tautomers Page 520. (You know this already just review if necessary.) Induced mutations Oxidatively damaged bases.  To avoid this type of damage, take antioxidants, 
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Ch 15 Notes - C15Mutation(DRAFT)...

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