2009/3/19113. Structure Determination: Nuclear Magnetic Resonance Spectroscopy核磁共振光譜學Based on McMurry’s Organic Chemistry, 7theditionWhat can we have from …Mass spectrometry (MS)molecular size and formula 大小與反應式Infrared (IR) spectroscopyfunctional groups 官能基Nuclear magnetic resonance spectroscopymap of carbon-hydrogen framework 碳氫關係Ultraviolet-visible spectroscopy (VIS)conjugated πelectron system 共軛雙鍵
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2009/3/192The Use of NMR SpectroscopyUsed to determinerelative location of atoms within a moleculeMost helpful spectroscopic technique in organic chemistryRelated to MRI in medicine (Magnetic Resonance Imaging磁共振成像)A MRI uses radio waves and a magnetic field to3A MRI uses radio waves and a magnetic field to take pictures of soft tissues, organs and bonesWhy This Chapter?NMR is the most valuable spectroscopic techniq esed for str ct re determinationtechnique used for structure determinationMore advanced NMR techniques are used in biological chemistry to study protein4biological chemistry to study protein structure and folding