Lec 2 - Fertilization Lecture set #2 Humunculus Early...

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1 “Humunculus” Early observers (1694) of human sperm thought that a tiny human was contained in the sperm head…. “Fertilization” Lecture set #2 Visualizing the calcium release in a sea urchin egg at fertilization. Figure 4.5 Stages of egg maturation at the time of sperm entry in different animal species
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2 Four Major Activities of Fertilization 1. Contact and recognition between gametes Quality control -sperm has to find the egg, penetrate outer layers, undergo acrosome reaction in order to bind and fuse with egg plasma membrane. These processes serve as examples of specific recognition and binding events, and signaling events that have lessons for other aspects of development. 2. Blocks to polyspermy Quantity control - only one sperm can enter Fast block - electrical, transient; provides time for permanent block to occur Slow block - mechanical, permanent 3. Fusion of genetic material (pronuclei) --> “syngamy” 4. Activation of metabolism and cell cycle re entry Figure 4.4 Structure of the sea urchin egg at fertilization
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This note was uploaded on 11/11/2010 for the course MCDB 112 taught by Professor Staff during the Spring '08 term at UCSB.

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Lec 2 - Fertilization Lecture set #2 Humunculus Early...

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