Lec 5 - 1 Lecture Set #5 Axis specification in Drosophila...

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Unformatted text preview: 1 Lecture Set #5 Axis specification in Drosophila (Ch 6 in 9e, Ch 9 in 8e) Outline 1. The syncytial embryo 2. Anterior-Posterior Axis Specification a. overview of gene cascade b. two major genetic pathways (maternal) c. current model 3. Dorsal-ventral axis specification Figure 6.1 Laser confocal micrographs of stained chromatin showing superficial cleavage in a Drosophila embryo 2 Figure 6.3 Formation of the cellular blastoderm in Drosophila Figure 6.6 Comparison of larval (left) and adult (right) segmentation in Drosophila (Part 1) 3 Figure 6.17 Generalized model of Drosophila anterior-posterior pattern formation Maternal Effect gene BICOID (note A-P gradient) Gap gene Hunchback (orange) Kruppel (green) (note overlap) Pair-rule gene Fushi-tarazu (seven bands) Segment polarity gene Engrailed (14 units) Figure 6.7 The anterior-posterior axis is specified during oogenesis 4 Figure 6.17 Generalized model of Drosophila anterior-posterior pattern formation Maternal Effect gene BICOID...
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This note was uploaded on 11/11/2010 for the course MCDB 112 taught by Professor Staff during the Spring '08 term at UCSB.

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Lec 5 - 1 Lecture Set #5 Axis specification in Drosophila...

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