genetics - 1. Given: Kan and Dozy and associates...

Info iconThis preview shows pages 1–3. Sign up to view the full content.

View Full Document Right Arrow Icon
1. Given: Kan and Dozy and associates investigated whether a RFLP could account for differences between the Hb A form of hemoglobin and the Hb S form of hemoglobin. The premises of their experiment is based the following TRUE statements. A) The founder of disease has RFLP near mutant allele for sickle cell disease B) Because RFLP is near the mutant allele, the possibility for crossing over near RFLP is slim. C) Molecular marker must be located next to the wild-type allele D) A and B are true only E) All of the above are true 2. A restriction fragment length polymorphism: A) Results when an individual has a different number of palindromes cleaved in a restriction enzyme when compared to other individuals B) Can be used to find the map distance between recombinant and nonrecombinant alleles C) Is made synthetically by EcoRI enzymes only D) A and B only E) All of the above are true 3. Which of the following experimental techniques is an example of cytogenetic mapping? A) Shotgun sequencing B) Choromosome walking C) Fluorescent in situ hybridization D) Pulse-field gel electrophoresis E) Restriction fragment length polymorphisms(RFLP) 4. If a researcher wants to separate a chromosome from a group of larger chromosomes or isolate a piece of chromosome, she / he would use: A) Fluorescent in situ hybridization B) Contigs
Background image of page 1

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
C) Physical mapping D) Pulse-field gel electrophoresis E) Two dimensional gel electrophoresis 5. A __________ is constructed when a DNA sequence is amplified by primers with polymerase chain reaction. A) Contig B) Sequence tagged site C) Isoelectric point D) Microsatellite E) A and D only 6. To make a physical map of a chromosome, the researcher needs to make a _____________ from a chromosome such that the clones put into vectors are contiguous overlapping pieces of chromosomal DNA. A) Sequence tagged site
Background image of page 2
Image of page 3
This is the end of the preview. Sign up to access the rest of the document.

Page1 / 8

genetics - 1. Given: Kan and Dozy and associates...

This preview shows document pages 1 - 3. Sign up to view the full document.

View Full Document Right Arrow Icon
Ask a homework question - tutors are online