Lecture6 - How is energy stored as reductive power (NADH)...

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1 How is energy stored as reductive power (NADH) converted to the energy currency ATP? Glycolysis, PDH and TCA have gained only 4 ATP equivalents by substrate level phosphorylation, but 10 NADH and 2 FADH2 as electron carriers. Turn redox energy NADH into chemical energy ATP using oxygen as final electron acceptor ( aerobic ). Oxidative Phosphorylation NADH ~~> ATP O 2 H 2 O ETC Electron transport chain and oxidative phosphorylation
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The mitochondrion is the cell‘s power house Contains: 1. PDH 2. TCA 3. (fatty acid oxidation) 4. ETC 5. oxidative phosphorylation Oxidative phosphorylation The Mitchell chemiosmotic theorem Chemical coupling hypothesis – discarded Activated protein hypothesis – discarded Mitchell hypothesis 1 st idea Protons are pumped across inner membrane 2 nd idea ATP synthase is driven by reverse proton flow using electrochemical free energy. 3 rd idea Carrier proteins mediate transport of essential compounds. 4
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Lecture6 - How is energy stored as reductive power (NADH)...

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