21_Chromosome inheritance III_forupload

21_Chromosome inheritance III_forupload - The Chromosomal...

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Unformatted text preview: The Chromosomal Basis of Inheritance X inactivation in Female Mammals In mammalian females, one of the two X chromosomes in each cell is randomly inactivated during embryonic development If a female is heterozygous for a particular gene located on the X chromosome, she will be a mosaic for that character LE 15-11 Early embryo: X chromosomes Allele for orange fur Cell division and X chromosome inactivation Allele for black fur Active X Inactive X Inactive X Black fur Orange fur Active X Two cell populations in adult cat: X inactivation in Female Mammals Alterations of chromosome number or structure cause some genetic disorders Large-scale chromosomal alterations often lead to spontaneous abortions (miscarriages) or cause a variety of developmental disorders Abnormal Chromosome Number In nondisjunction , pairs of homologous chromosomes do not separate normally during meiosis As a result, one gamete receives two of the same type of chromosome, and another gamete receives no copy...
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21_Chromosome inheritance III_forupload - The Chromosomal...

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